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Helge Eilers, M.D.
Associate Professor of Clinical Anesthesia
Department of Anesthesia and Perioperative Care
Contact Information
| Academic Office 513 Parnassus Ave. Rm S436 Campus Box 0427 Telephone: 415-514-3785 eilersh@anesthesia.ucsf.edu |
BiographyEducation
- 1993, Rheinische Friedrich-Wilhelms-Universitaet, Bonn, Germany, M.D
Residencies
- 1993-1995, University Hospital, University of Cologne, Germany, Resident, Anesthesiology
- 1997-1998, Boise VA Medical Center, Boise, Idaho, Intern
- 1998-2001, University of California, San Francisco, Resident, Anesthesia and Perioperative Care
Fellowships
- 1995-1997, University of California San Francisco, Postdoctoral Research Fellow
Board Certification
- American Board of Anesthesiology
Program Affiliations
- Department of Anesthesia and Perioperative Care
- Department of Surgery, Division of Transplantation
Clinical Expertise
- Kidney Transplantation
- Liver Transplantation
- Pancreas Transplantation
Research Interests
- Anesthetic effect on peripheral nociceptors
- Chronic Kidney Disease
- Ion channels in peripheral nociceptors
- Liver Transplantation
- Mechanical nociception
- Molecular mechanisms of anesthetic action
- Molecular mechanisms of peripheral pain transduction
Biography
Dr Eilers attends as anesthesiologist in the Moffitt-Long and Mt. Zion operating rooms specializing on anesthesia for liver transplantation. He earned his medical degree at University of Bonn in Germany and completed a postdoctoral research fellowship in the laboratory of Dr. Philip Bickler at UCSF. He continued his career at UCSF as a resident and is currently an assistant professor and attending physician in the Department of Anesthesia and Perioperative Care.
Research Summary
Dr Eilers is involved in a number of research projects focused on the advancement of our understanding of the molecular mechanisms responsible for the transduction of painful stimuli in peripheral nociceptive neurons. His main effort is currently directed at investigating the effects of general anesthetics in peripheral nociceptors. Irritant anesthetics such as isoflurane have been shown to activate sensory neurons and may contribute to the severity of postoperative pain.
Selected Publications
- Eilers H, Cattaruzza F, Nassini R, Materazzi S, Andre E, Chu C, Cottrell GS, Schumacher M, Geppetti P, Bunnett NW. "Pungent general anesthetics activate transient receptor potential-A1 to produce hyperalgesia and neurogenic bronchoconstriction." Anesthesiology. 112(6):1452-63 (2010).
- Eilers H. "Anesthetic activation of nociceptors: adding insult to injury?" Mol Interv 8:226-9; (2008).
- Eilers H, Lee SY, Hau CW, Logvinova A, Schumacher MA. "The rat vanilloid receptor splice variant VR.5'sv blocks TRPV1 activation." Neuroreport 18: 969-73 (2007).
- Eilers H, Trilk SL, Lee SY, Xue Q, Jong BE, Moff I, Levine JD, Schumacher MA. "Isolation of an mRNA binding protein homologue that is expressed in nociceptors." Eur J Neurosci 20:2283-93 (2004).
