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Claus U. Niemann, M.D.

Claus U. Niemann, M.D.

Professor of Anesthesia and Surgery

Department of Anesthesia & Perioperative Care
Department of Surgery

Co-Director, Ischemic Organ Injury Lab

Contact Information

University of California, San Francisco
500 Parnassus MUE 4th Floor
Box 0648
San Francisco, Ca 94143-0648
Tel: 415-502-2162
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  • 1986-93, Ludwig-Maximilians University, Munich, Germany, M.D.
  • 1993-94  Intern ;  City Hospital St. Georg,, University of Hamburg, Germany and Klinikum Grosshadern, Ludwig-Maximilians University, Munich, Germany
  • 1996-99, University of California, San Francisco, Resident, Anesthesia
  • 1999-01, University of California, San Francisco, Fellow, Liver Transplant Research
  • 1994-96, Department of Anesthesiology, Northwestern University, Chicago, Illinois, Fellow, Postdoctoral Research
  • American Board of Anesthesiology
  • Department of Anesthesia and Perioperative Care
  • Department of Surgery, Division of Transplantation
  • UCSF Liver Center
  • Kidney Transplantation
  • Liver Transplantation
  • Pancreas Transplantation
  • View Research Profile at UCSF Clinical & Translational Science Institute

  • Inflammatory response to injuryIschemia reperfusion injury
  • Intensive Insulin Therapy in Deceased Donors-to improve renal allograft function and transplanted allograft outcomes
  • Liver transplantation
  • Metabolomics
  • Organ donation
  • Renal and hepatic injury during surgery

My group is interested in identifying why obese individuals are at greater risk of liver injury in the setting of trauma or surgery. My long-term goal is to understand the relationship between metabolic and immunologic processes in the liver. One potential link between these underlying mechanisms could be the peptide leptin, which can profoundly modify inflammatory and metabolic pathways. The goal of this research effort is to improve understanding of the impact of leptin on acute inflammatory cascade and metabolic response during hepatic ischemia-reperfusion. This will benefit patients by improving risk-stratification of candidates for hepatic surgery and possibly lead to preventive therapies for ischemia-reperfusion injury. 

Study ID: Deceased Organ Donor Interventions to Protect Kidney Graft Function
Most recent publications from a total of 84
  1. Schaeffer DB, Constantin CG, Bondarenko AS, Everson ET, Niemann C. Spatially resolved Thomson scattering measurements of the transition from the collective to the non-collective regime in a laser-produced plasma. Rev Sci Instrum. 2016 Nov; 87(11):11E701. View in PubMed
  2. Levitsky J, O'Leary JG, Asrani S, Sharma P, Fung J, Wiseman A, Niemann CU. Protecting the Kidney in Liver Transplant Recipients: Practice-Based Recommendations From the American Society of Transplantation Liver and Intestine Community of Practice. Am J Transplant. 2016 Sep; 16(9):2532-44. View in PubMed
  3. Klok FA, Niemann C, Dellas C, Hasenfuß G, Konstantinides S, Lankeit M. Performance of five different bleeding-prediction scores in patients with acute pulmonary embolism. J Thromb Thrombolysis. 2016 Feb; 41(2):312-20. View in PubMed
  4. Niemann CU, Malinoski D. Therapeutic Hypothermia in Deceased Organ Donors and Kidney-Graft Function. N Engl J Med. 2015 Dec 31; 373(27):2687. View in PubMed
  5. Olmos A, Feiner J, Hirose R, Swain S, Blasi A, Roberts JP, Niemann CU. Impact of a quality improvement project on deceased organ donor management. Prog Transplant. 2015 Dec; 25(4):351-60. View in PubMed
  6. Niemann CU, Feiner J, Swain S, Bunting S, Friedman M, Crutchfield M, Broglio K, Hirose R, Roberts JP, Malinoski D. Therapeutic Hypothermia in Deceased Organ Donors and Kidney-Graft Function. N Engl J Med. 2015 Jul 30; 373(5):405-14. View in PubMed
  7. Kotloff RM, Blosser S, Fulda GJ, Malinoski D, Ahya VN, Angel L, Byrnes MC, DeVita MA, Grissom TE, Halpern SD, Nakagawa TA, Stock PG, Sudan DL, Wood KE, Anillo SJ, Bleck TP, Eidbo EE, Fowler RA, Glazier AK, Gries C, Hasz R, Herr D, Khan A, Landsberg D, Lebovitz DJ, Levine DJ, Mathur M, Naik P, Niemann CU, Nunley DR, O'Connor KJ, Pelletier SJ, Rahman O, Ranjan D, Salim A, Sawyer RG, Shafer T, Sonneti D, Spiro P, Valapour M, Vikraman-Sushama D, Whelan TP. Management of the Potential Organ Donor in the ICU: Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Consensus Statement. Crit Care Med. 2015 Jun; 43(6):1291-325. View in PubMed
  8. Patel MS, Niemann CU, Sally MB, De La Cruz S, Zatarain J, Ewing T, Crutchfield M, Enestvedt CK, Malinoski DJ. The Impact of Hydroxyethyl Starch Use in Deceased Organ Donors on the Development of Delayed Graft Function in Kidney Transplant Recipients: A Propensity-Adjusted Analysis. Am J Transplant. 2015 Aug; 15(8):2152-8. View in PubMed
  9. Clark SE, Everson ET, Schaeffer DB, Bondarenko AS, Constantin CG, Niemann C, Winske D. Enhanced collisionless shock formation in a magnetized plasma containing a density gradient. Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Oct; 90(4):041101. View in PubMed
  10. Niemann CU. Abdominal transplantation. Anesthesiol Clin. 2013 Dec; 31(4):ix-x. View in PubMed
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