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Melvin B. Heyman, M.D., M.P.H.

Melvin B. Heyman, M.D., M.P.H.

Professor of Pediatrics
Chief, Division of Pediatric Gastroenterology, Hepatology and Nutrition
Department of Pediatrics
Director, Pediatric Inflammatory Bowel Disease Program 

Contact Information

Academic Office
Melvin B Heyman, MD, MPH
500 Parnassus Ave, MU 4-East
Campus Box 0136
University of California, San Francisco
San Francisco, CA   94143-0136
mheyman@peds.ucsf.edu
Intestinal Rehabilitation and Transplantation Program
400 Parnassus Ave., 2nd Floor
San Francisco, CA 94143
Phone: (877) 762-6935

Gastroenterology and Liver
400 Parnassus Ave., Second Floor
San Francisco, CA 94143
Phone: (415) 353-2813
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  • UCLA School of Medicine 1976
  • LAC/USC Medical Center, Pediatrics 1979
  • UCLA Medical Center, Gastroenterology and Nutrition 1981
  • American Board of Pediatrics, General Pediatrics, Pediatric Gastroenterology Subspecialty
  • Gastroesophageal Reflux Disease
  • Inflammatory Bowel Disease
  • Intestinal Failure
  • Intestinal Transplantation
  • Liver Transplantation
  • Short Bowel Syndrome

Dr. Melvin B. Heyman, chief of pediatric gastroenterology, hepatology and nutrition at UCSF Benioff Children's Hospital, specializes in treating children with inflammatory bowel disease, including Crohn's disease and ulcerative colitis, and nutrition-related problems. He earned a medical degree at UCLA and completed a pediatric residency at Los Angeles County-University of Southern California Medical Center. He also completed postdoctoral training in nutrition, earned a master's degree in public health, and completed a fellowship in pediatric gastroenterology at UCLA. In 1981, he joined UCSF, where he organized the pediatric nutrition support service and established protocols for pediatric gastroenterology.

A UCSF professor of pediatrics, Dr. Heyman is chair of the executive committee of the Pediatric Gastroenterology and Nutrition section of the American Academy of Pediatrics. He also serves on many local and national committees, including the American Academy of Pediatrics' Task Force on Prevention of Obesity in School Health (POSH),  and the National Board of the National PTA. Dr. Heyman has an active role in teaching at all levels. He is the principal investigator for the NIH Training Grant that funds the Training Program in Pediatric Gastroenterology and Nutrition at UCSF.

Dr. Heyman's research has been oriented towards clinical problems in pediatric patients with nutrition and/or gastroenterologic issues. He was one of the first investigators to reveal the importance of nutrition support in sickle cell anemia, helped to develop procedures in the diagnosis of hepatobiliary problems in infants, and has been actively pursuing novel treatments for children with inflammatory bowel disease and gastroesophageal reflux disease.

His research has been funded by the NIH, by foundation grants, and by pharmaceutical and formula industry support.  His recent research has been evolving into investigation of obesity in infancy and in school age children.  With other members of COAST, he is looking at the effects of acculturation in the Latino and the Chinese populations in San Francisco.  He is also very actively involved in developing strategies to improve nutrition and physical activities in public schools.

Most recent publications from a total of 145
  1. Somineni HK, Venkateswaran S, Kilaru V, Marigorta UM, Mo A, Okou DT, Kellermayer R, Mondal K, Cobb D, Walters TD, Griffiths A, Noe JD, Crandall WV, Rosh JR, Mack DR, Heyman MB, Baker SS, Stephens MC, Baldassano RN, Markowitz JF, Dubinsky MC, Cho J, Hyams JS, Denson LA, Gibson G, Cutler DJ, Conneely KN, Smith AK, Kugathasan S. Blood-derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation. Gastroenterology. 2019 Feb 16. View in PubMed
  2. Hagiwara SI, Hasdemir B, Heyman MB, Chang L, Bhargava A. Plasma Corticotropin-Releasing Factor Receptors and B7-2? Extracellular Vesicles in Blood Correlate with Irritable Bowel Syndrome Disease Severity. Cells. 2019 Jan 30; 8(2). View in PubMed
  3. Haberman Y, Karns R, Dexheimer PJ, Schirmer M, Somekh J, Jurickova I, Braun T, Novak E, Bauman L, Collins MH, Mo A, Rosen MJ, Bonkowski E, Gotman N, Marquis A, Nistel M, Rufo PA, Baker SS, Sauer CG, Markowitz J, Pfefferkorn MD, Rosh JR, Boyle BM, Mack DR, Baldassano RN, Shah S, Leleiko NS, Heyman MB, Grifiths AM, Patel AS, Noe JD, Aronow BJ, Kugathasan S, Walters TD, Gibson G, Thomas SD, Mollen K, Shen-Orr S, Huttenhower C, Xavier RJ, Hyams JS, Denson LA. Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response. Nat Commun. 2019 01 03; 10(1):38. View in PubMed
  4. Krishnakumar C, Ballengee CR, Liu C, Kim MO, Baker SS, Baldassano RN, Cohen SA, Crandall WV, Denson LA, Dubinsky MC, Evans J, Gokhale R, Griffiths A, Guthery SL, Oliva-Hemker M, Heyman MB, Keljo D, Kellermayer R, Leleiko NS, Mack DR, Markowitz JF, Moulton DE, Noe JD, Otley AR, Patel AS, Pfefferkorn M, Rabizadeh S, Rosh JR, Snapper S, Walters TD, Ziring D, Mondal K, Kappelman MD, Hyams JS, Kugathasan S. Variation in Care in the Management of Children With Crohn's Disease: Data From a Multicenter Inception Cohort Study. Inflamm Bowel Dis. 2019 Jan 02. View in PubMed
  5. Fernandes MA, Verstraete SG, Phan TG, Deng X, Stekol E, LaMere B, Lynch SV, Heyman MB, Delwart E. Enteric Virome and Bacterial Microbiota in Children With Ulcerative Colitis and Crohn Disease. J Pediatr Gastroenterol Nutr. 2019 Jan; 68(1):30-36. View in PubMed
  6. Heyman MB, Weiss P, Boyer D, Fussell J, Imundo L, Aye T, Jarjour IT, Spicer R, Bale J. Challenges of Funding Pediatric Fellowship Programs-Invited Commentary from the Council of Pediatric Subspecialties. J Pediatr. 2019 Jan; 204:4-6.e1. View in PubMed
  7. Haberman Y, Schirmer M, Dexheimer PJ, Karns R, Braun T, Kim MO, Walters TD, Baldassano RN, Noe JD, Rosh J, Markowitz J, Crandall WV, Mack DR, Griffiths AM, Heyman MB, Baker SS, Kellermayer R, Moulton D, Patel AS, Gulati AS, Steiner SJ, LeLeiko N, Otley A, Oliva-Hemker M, Ziring D, Kirschner BS, Keljo DJ, Guthery SL, Cohen SA, Snapper S, Evans J, Dubinsky M, Aronow B, Hyams JS, Kugathasan S, Huttenhower C, Xavier RJ, Denson LA. Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis. Mucosal Immunol. 2019 Mar; 12(2):491-502. View in PubMed
  8. Uc A, Perito ER, Pohl JF, Shah U, Abu-El-Haija M, Barth B, Bellin MD, Ellery KM, Fishman DS, Gariepy CE, Giefer MJ, Gonska T, Heyman MB, Himes RW, Husain SZ, Maqbool A, Mascarenhas MR, McFerron BA, Morinville VD, Lin TK, Liu QY, Nathan JD, Rhee SJ, Ooi CY, Sellers ZM, Schwarzenberg SJ, Serrano J, Troendle DM, Werlin SL, Wilschanski M, Zheng Y, Yuan Y, Lowe ME. INternational Study Group of Pediatric Pancreatitis: In Search for a CuRE Cohort Study: Design and Rationale for INSPPIRE 2 From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec; 47(10):1222-1228. View in PubMed
  9. Schirmer M, Denson L, Vlamakis H, Franzosa EA, Thomas S, Gotman NM, Rufo P, Baker SS, Sauer C, Markowitz J, Pfefferkorn M, Oliva-Hemker M, Rosh J, Otley A, Boyle B, Mack D, Baldassano R, Keljo D, LeLeiko N, Heyman M, Griffiths A, Patel AS, Noe J, Kugathasan S, Walters T, Huttenhower C, Hyams J, Xavier RJ. Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course. Cell Host Microbe. 2018 10 10; 24(4):600-610.e4. View in PubMed
  10. Lindoso L, Mondal K, Venkateswaran S, Somineni HK, Ballengee C, Walters TD, Griffiths A, Noe JD, Crandall W, Snapper S, Rabizadeh S, Rosh JR, LeLeiko N, Guthery S, Mack D, Kellermayer R, Gulati AS, Pfefferkorn MD, Moulton DE, Keljo D, Cohen S, Oliva-Hemker M, Heyman MB, Otley A, Baker SS, Evans JS, Kirschner BS, Patel AS, Ziring D, Stephens MC, Baldassano R, Dubinsky MC, Markowitz J, Denson LA, Hyams J, Kugathasan S, Ananthakrishnan AN. The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children. Am J Gastroenterol. 2018 Oct; 113(10):1524-1529. View in PubMed
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