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LiverSource »  Faculty »  Program Leadership »  Nancy L. Ascher, M.D., Ph.D.

Nancy L. Ascher, M.D., Ph.D.

  • Professor of Surgery
  • Division of Transplant Surgery
  • Isis Distinguished Professor in Transplantation

Contact Information

Academic Office
415-353-9321
[email protected]
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  • University of Michigan, Ann Arbor, MI, B.A., 1967-70
  • University of Michigan Medical School, Ann Arbor, MI, M.D., 1970-74
  • University of Minnesota, Minneapolis, MN, Ph.D., 1974-85
  • University of Minnesota, Department of Surgery, Minneapolis, MN,  Surgical Internship, 1974-75
  • University of Minnesota, Department of Surgery, Minneapolis, MN, Surgical Residency, 1975-77
  • University of Minnesota, Department of Surgery, Minneapolis, MN, Surgical Residency, 1979-81
  • University of Minnesota, Department of Surgery, Minneapolis, MN,   Transplant Fellowship, 1981-1982
  • University of Minnesota, Department of Surgery, Minneapolis, MN, Research Fellowship, 1977-79
  • American Board of Surgery, 1982, renewed 2012
  • End-Stage Kidney Disease
  • Fulminant Hepatic Failure
  • Hepatitis B
  • Hepatitis C
  • Hepatocellular Carcinoma (Liver Cancer)
  • Kidney Transplantation
  • Liver Cysts
  • Liver Transplantation
  • Living Donor Liver Transplantation
  • Living Donor Kidney Transplantation
  • Non-alcoholic Fatty Liver Disease
  • Pediatric Kidney Transplantation
  • Pediatric Liver Transplantation
  • Portal Hypertension
  • Clinical Transplantation
  • Recurrence After Liver Transplantation
  • Transplant Ethics
  • Transplant Policy

Dr. Nancy Ascher has devoted her career to organ transplants and transplant research. Dr. Ascher completed her undergraduate and medical education at the University of Michigan, Ann Arbor. She then went on to complete a general surgery residency and clinical transplantation fellowship at the University of Minnesota. 

Dr. Ascher joined the faculty of the Department of Surgery at the University of Minnesota in 1982 and was named Clinical Director of the Liver Transplant Program. She was recruited in 1988 by the UCSF Department of Surgery to build a liver transplantation program. In 1991, she was appointed Chief of Transplantation, an expanded role that included liver, kidney and pancreas transplants.

In 1993, Dr. Ascher was appointed Vice-Chair of the UCSF Department of Surgery, and in 1999 was appointed Department Chair where she served until September 2016.

Dr. Ascher has had a distinguished career of public service that includes appointments to the Presidential Task Force on Organ Transplantation and the Surgeon General's Task Force on Increasing Donor Organs. She also served as Chair of the Advisory Committee on Organ Transplantation for the Secretary of Health and Human Services from 2001 - 2005. Highly respected by her peers, Dr. Ascher was named to the list of U.S. News "America's Top Doctors," a distinction reserved for the top 1% of physicians in the nation for a given specialty.

Dr. Ascher is a Fellow of the American College of Surgeons and holds memberships in numerous other medical societies. She has taken an active leadership role in American Society of Transplant Surgeons activities and was its past-president. Dr. Ascher has published over 425 articles in medical and scientific journals. Her research interests are in hepatocyte immunogenicity, mechanisms of allograft rejection and clinical transplantation.

I. RECURRENT DISEASE AFTER LIVER TRANSPLANT
The NIH Liver Transplant Data Base has been extended to address the important issue of disease recurrence after liver transplantation. Although short term liver transplant results have improved markedly over the past ten years, it is apparent that disease recurrence is an important source of patient morbidity and graft loss. Long term following of greater than 1000 patients in the Liver Transplant Data Base will facilitate our understanding of the factors associated with graft recurrence.

II. EXPANDED CRITERIA FOR LIVER TRANSPLANT FOR HEPATOCELLULAR CARCINOMA
We have redefined the criteria for liver transplantation beyond the Milan criteria. The UCSF criteria enables additional patients to benefit from liver transplants without compromising outcome.

Data provided by UCSF Profiles, powered by CTSI
  • LIVER TRANSPLANTATION CENTERS
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    Jan 1990
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    Dec 1997
    Principal Investigator
  • ALLOGRAFT RESPONSE TO LIVER TISSUE
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    Funding Period:
    Sep 1988
    -
    Sep 1995
    Principal Investigator
  • ORGAN TRANSPLANTS: ANALYSIS OF MIGRATING LYMPHOCYTES
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    Jul 1984
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    Jun 1987
    Principal Investigator
MOST RECENT PUBLICATIONS FROM A TOTAL OF 424
Data provided by UCSF Profiles, powered by CTSI
  1. Chadha R, Sakai T, Rajakumar A, Shingina A, Yoon U, Patel D, Spiro M, Bhangui P, Sun LY, Humar A, Bezinover D, Findlay J, Saigal S, Singh S, Yi NJ, Rodriguez-Davalos M, Kumar L, Kumaran V, Agarwal S, Berlakovich G, Egawa H, Lerut J, Clemens Broering D, Berenguer M, Cattral M, Clavien PA, Chen CL, Shah S, Zhu ZJ, Ascher N, Bhangui P, Rammohan A, Emond J, Rela M. Anesthesia and Critical Care for the Prediction and Prevention for Small-for-size Syndrome: Guidelines from the ILTS-iLDLT-LTSI Consensus Conference. Transplantation. 2023 10 01; 107(10):2216-2225. View in PubMed
  2. Kow AWC, Liu J, Patel MS, De Martin E, Reddy MS, Soejima Y, Syn N, Watt K, Xia Q, Saraf N, Kamel R, Nasralla D, McKenna G, Srinvasan P, Elsabbagh AM, Pamecha V, Palaniappan K, Mas V, Tokat Y, Asthana S, Cherukuru R, Egawa H, Lerut J, Broering D, Berenguer M, Cattral M, Clavien PA, Chen CL, Shah S, Zhu ZJ, Emond J, Ascher N, Rammohan A, Bhangui P, Rela M, Kim DS, Ikegami T, ILTS-iLDLT-LTSI SFSS Working Group. Post Living Donor Liver Transplantation Small-for-size Syndrome: Definitions, Timelines, Biochemical, and Clinical Factors for Diagnosis: Guidelines From the ILTS-iLDLT-LTSI Consensus Conference. Transplantation. 2023 10 01; 107(10):2226-2237. View in PubMed
  3. Kirchner VA, Shankar S, Victor DW, Tanaka T, Goldaracena N, Troisi RI, Olthoff KM, Kim JM, Pomfret EA, Heaton N, Polak WG, Shukla A, Mohanka R, Balci D, Ghobrial M, Gupta S, Maluf D, Fung JJ, Eguchi S, Roberts J, Eghtesad B, Selzner M, Prasad R, Kasahara M, Egawa H, Lerut J, Broering D, Berenguer M, Cattral MS, Clavien PA, Chen CL, Shah SR, Zhu ZJ, Ascher N, Ikegami T, Bhangui P, Rammohan A, Emond JC, Rela M. Management of Established Small-for-size Syndrome in Post Living Donor Liver Transplantation: Medical, Radiological, and Surgical Interventions: Guidelines From the ILTS-iLDLT-LTSI Consensus Conference. Transplantation. 2023 10 01; 107(10):2238-2246. View in PubMed
  4. Meier RPH, Nunez M, Syed SM, Feng S, Tavakol M, Freise CE, Roberts JP, Ascher NL, Hirose R, Roll GR. DCD liver transplant in patients with a MELD over 35. Front Immunol. 2023; 14:1246867. View in PubMed
  5. Hakeem AR, Mathew JS, Aunés CV, Mazzola A, Alconchel F, Yoon YI, Testa G, Selzner N, Sarin SK, Lee KW, Soin A, Pomposelli J, Menon K, Goyal N, Kota V, Abu-Gazala S, Rodriguez-Davalos M, Rajalingam R, Kapoor D, Durand F, Kamath P, Jothimani D, Sudhindran S, Vij V, Yoshizumi T, Egawa H, Lerut J, Broering D, Berenguer M, Cattral M, Clavien PA, Chen CL, Shah S, Zhu ZJ, Ascher N, Bhangui P, Rammohan A, Emond J, Rela M. Preventing Small-for-size Syndrome in Living Donor Liver Transplantation: Guidelines From the ILTS-iLDLT-LTSI Consensus Conference. Transplantation. 2023 10 01; 107(10):2203-2215. View in PubMed
  6. View All Publications

 

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